Proposals will be solicited in specific focus areas:
HUMAN RESOURCES, LEARNING AND DEVELOPMENT (HLD) Develop and retain staff through game-changing learning and development initiatives.
MEDICAL RESEARCH AND DEVELOPMENT (MRD) Support medical R&D projects that give priority to the needs of the populations MSF assists.
OPERATIONS IMPROVEMENTS AND TECHNOLOGY (OIT) Strengthen MSF operational capacity; adopt state-of-the-art practices, tools and technology to improve field work.
EFFICIENCY GAINS (EFG) Implement cost reduction initiatives to minimize duplication and free up funds and people to focus on social mission.
ACCESS (ACC) Improve the accessibility, availability, affordability, appropriateness, and quality of products for health care for populations and communities MSF assists.
The TIC will consider proposals outside these areas where a strong rationale/business case is presented.
INCUBATOR PROJECTS Incubator projects include investments under €250,000. These projects may start small but have the potential to scale to major transformational projects.
LARGE-SCALE PROJECTS Large-scale project include investments greater than €250,000 but less than €2.5M.
VERY-LARGE-SCALE PROJECTS Very-Large-Scale projects include investments of €2.5M or more.
Project Dashboard
The TIC Project Dashboard will provide information on proposals reviewed by the Secretariat and Selection Committee – including a breakdown of projects by focus areas, category (incubator, large-scale, or very-large scale), and total number of accepted projects. Once available, information on approved projects and completed projects, including project status and outcomes, will be shared.
82
Incubator
18
Large-scale
3
Very-Large-scale
23
Human Resources Learning and Development
28
Medical Research and Development
37
Operational Improvements and Technology
16
Efficiency Gains
2
Access Fund
16
Other
* Information will be updated on a periodic basis, following Selection Committee and ExCom meetings.
See the section Projects on the Go (below) for a list of projects that have been accepted for TIC funding.
Concept Notes, Business Cases, status reports, and videos for submitted projects are available on our SharePoint site (for those with an MSF e-mail address only).
Projects on the Go
Prove the viability and usefulness of democratizing the availability of 3D printing capacity in MSF projects by providing 3D printers and the related procedures, protocols and support to any field project that requests it. Focus on 3 field projects to test-and-learn and establish a repository of downloadable and printable medical and none medical products such as prosthetics, humeral braces and adaptors. Includes designing a service to model new custom-made objects on request and explores the possibility of defining workflows for rapid local manufacturing in response to emergencies.
Address significant gaps in patient access to life-saving treatment for patients with Type 1 Diabetes (T1D) by creating a model of care that supports patient empowerment and autonomy. Provide home-based insulin pens and blood sugar monitoring devices to patients who often need to travel great distances and face dangers in accessing MSF clinics. Develop a comprehensive package with training, patient education tools, monitoring strategies, and improved commodities. The model will be piloted in 2 OCP projects: Carnot (CAR) and Aweil (South Sudan) to assess its feasibility and strengthen patient engagement.
Approximately 1.3 million new HIV infections occur globally each year. More than half occur among marginalised populations facing persistent barriers to accessing health services and effective prevention options. Long-acting injectable lenacapavir (LEN-LA) could transform HIV prevention delivery but access is at serious risk due to restrictive voluntary licensing that excludes many middle-income countries, unaffordable pricing, regulatory and supply delays, growing politicisation of access for vulnerable populations, and severe reductions in global HIV funding. Without coordinated and timely action, LEN-LA risks remaining inaccessible to those who need it most. A TIC-supported HIV PrEP Incubator (20242025) established the “LEN-LA for All” civil society collective and implemented coordinated advocacy on licensing, pricing, and rollout strategies across priority countries. Building on this critical groundwork, the ACCESS-LA project aims to translate this momentum into equitable scale by implementing a multipronged approach that integrates civil society–led advocacy to improve access conditions, targeted support to MSF operations to introduce LEN-LA using community-led service delivery models, and evidence generation to inform policy decisions and sustainable scale-up for key and vulnerable populations.
Improve patient access to MSF’s health facilities by adapting, testing and implementing a World Bank developed interactive geographic accessibility model. The model assesses MSF programs’ coverage and heuristically determines best locations for health activities. Currently, catchment areas and travel distances to health sites are determined by linear distance proximity analyses. The new tool will consider multiple factors to increase access including 3D terrain analysis (mountains, walleyes and other obstacles), natural disasters (floods, collapsed infrastructure etc.) and conflict areas.
To accelerate AI developments and use across MSF, this project will establish an intersectional AI support team through the Information Management System (ISM) platform. The project will develop an infrastructure to host AI solutions in a centralized area, a risk-based framework to ensure appropriate use of AI, a targeted chatbot that can be rolled out to specific user groups, and an MSF-branded translation tool based on key languages which includes MSF-specific vocabulary.
Addressing structural racism has been identified as a priority for MSF, yet widespread lack of knowledge and understanding of racism limits our ability to hold conversations on racism. This project facilitates a discovery-based anti-racism journey and aims to increase knowledge and understanding of racism at MSF through training, resource-sharing and the creation of a conversation framework.
In the fight against Antimicrobial Resistance, this project is developing an open source and offline application, using artificial intelligence and machine learning, to improve clinical care of patients by supporting non-expert laboratory technicians measuring and interpreting Antibiotic Susceptibility Tests (AST) to help doctors prescribe accurate antibiotics to their patients and ultimately support the update of empirical treatment based on real etiology.
Adapt and improve MSF’s current approach in supporting affected patients and communities to self-advocate and take action, as part of a mutually beneficial process. Design, test, learn and establish conditions for scaling “building self-advocacy experts by experience”, strengthen accountability in patient/community inclusion. Provide a more holistic continuity of care and ‘quality of care’ as defined by patients and communities themselves.
The project aims to address frequent cold chain breakdowns experienced by MSF by bringing a new cold chain carrier to market. Following the prototype development of an innovative and portable cold chain carrier designed for MSF workers using cold chain transportation in remote areas, the project will focus on finalizing product development, preparing the product for commercialization, and validating its performance through field tests in various contexts, including vaccination, sample transportation, and laboratory reactive transportation.
Address the profound surgical care gap in Central African Republic (CAR) by designing training for General Practitioners (GPs) in essential surgical skills, that if implemented in the future, could establish a longer term locally driven mentorship program and make surgical services accessible in rural and underserved communities. With a surgeon to population ratio of only 0.36 per 100,000 over 100 times below the International minimum standards and maternal mortality rates at 882 per 100,000 live births, CAR faces a severe shortage in trained surgical personnel, with only 14 qualified surgeons in entire country. The project aims to conduct a series of workshops and need assessment with local stakeholders including the Ministry of Health (MOH) and Université de Bangui to assess and design a training program based on the real needs for GP suitable in local context. The program leverages MSF’s partnership with the University of British Columbia (UBC), Essential Surgical Task Sharing Program.
The project addresses MSF’s growing need for coherent digital content governance, efficient lifecycle management and sustainable storage to safeguard institutional knowledge and support future adaptability. As digital information volumes rise, fragmented processes, inconsistent governance and increasing storage requirements pose risks to operational efficiency, data security and knowledge preservation. The initiative will develop an information management governance blueprint and pilot an AI-enabled digital content lifecycle, archiving and preservation minimum viable product to ensure consistent standards, automated processing, and improved accessibility. By unifying information governance across operational directorates (ODs), the project strengthens MSF’s ability to preserve institutional memory, enhance operational efficiency, mitigate security and compliance risks, reduce costs and environmental impact, and empower teams with a reliable, future-proof digital knowledge ecosystem.
The project aims to strengthen MSF’s associative legitimacy and accountability to patients and communities in the Democratic Republic of Congo (DRC), one of MSF’s most complex and important operational contexts, with six ODs, supported by the intersectional liaison office (BALI), delivering large scale humanitarian and medical activities. MSF DRC with 1,000 active associative members, has a key mandate to represent community voices and anchor MSF actions in local society. However, the roles between the Association and ODs remain unclear, leading to blurred responsibilities. The project will strengthen MSF DRC’s associative role as a key contributor of accountability and associative governance in close collaboration with the ODs. By developing a shared governance framework, piloting a model in three locations, and strengthening associative capacity and partnership with civil society, it aims to explore a mechanism to integrate patients and community perspectives in MSF decision making process. It will produce a validated documented model aligned with SPARC priorities that strengthens trust, accountability, and serves as a replicable reference for the wider 27 MSF associations.
The project aims to strengthen MSF’s road safety and reduce its environmental footprint by creating a shared, intersectional eco and defensive driving program for all Operational Directorate (ODs). Globally MSF operates an estimated 2500 vehicles driven by 2400 MSF drivers, yet training remains fragmented, ad hoc, costly, and limited in reach e.g., training planned in 2025 by all ODs will reach only 9% of MSF drivers. In 2024, 185 road related incidents were reported across all ODs (including 35 moderate and 14 severe), and the MSF fleet consumed roughly 4 million liters of diesel annually. The project aims to establish a centralized training capacity for drivers hosted by one MSF entity, develop MSF tailored training package for contexts where external providers cannot operate, and organize a global pool of trainers able to deliver courses across MSF including in high insecure contexts. Pilot testing will be conducted across four diverse countries.
Building on a previous Phase I, which explored the potential for climate-related funding opportunities for MSF, the project aims to enable MSF to access new, non-cannibalizing funding streams for climate mitigation and adaptation in support of its medical humanitarian mission. Specific objectives include developing a clear narrative articulating MSF’s approach to addressing climate impact in humanitarian response, establishing the foundations for an international, cross-OD MSF climate fund, preparing MSF to engage credibly with climate focused donors and creating the conditions for scaling and transitioning to post-TIC management at international level.
Increase MSF’s field capacity to implement evidence-based decision-making and use high quality, robust scientific data by transforming the role of field epidemiologists trained specifically in the skills and competencies in MSF project contexts. Includes field epidemiologist training fellowship with an in-person 10-day introductory course followed by 4 remotely-conducted specialist modules that the epidemiologist can pursue while working in the field. Leverages use of 1) statistical software program, “R”; 2) surveillance; 3) epidemiological surveys; and 4) outbreak investigation.
The project aims to address the limitations in MSF’s current Field ICT ecosystem, which is fragmented across all seven Operational Directorates (ODs) and considered unfit to manage increasingly digital needs for MSF humanitarian operations. Currently, 474 Field Network Kits (FNKs) from different manufacturers and with different configurations are installed across different sites. Their architectural, performance, and lifecycle limitations prevent them from reliably supporting critical digital workflows such as electronic medical records, telemedicine, HR, finance, logistics and learning tools particularly in low connectivity contexts. To solve this, the project will design the next generation Field ICT ecosystem for all seven ODs. It will define common technical standards, produce a shared modern, resilient, offline capable, and secure architecture that enables convergence, interoperability and mutualization. In close coordination with ISM, it aims to deliver a blueprint for the movement through a phased approach covering needs assessment, technical design, prototype component sourcing, lab testing, field validation and transition planning towards implementation.
Addresses respiratory distress as one of the most common life-threatening presentations in neonates and children by deploying and testing Humidified High-Flow Nasal Oxygen (HFNO). Following positive experiences in Yemen, demonstrate that HFNO use in routine is feasible, scalable and could dramatically change care management for children suffering from respiratory distress. Scale up implementation of HFNO in 3 project sites: Sierra Leone for OCB and Afghanistan, Yemen or Bangladesh for OCP combined with operational research in collaboration with Epicentre.
Long acting, twice-yearly injectable Lenacapavir (LEN-LA) has proven superior HIV prevention efficacy and can be produced for as little as $40-100 per year, however the patent holder has a deeply restrictive pricing and access strategy. Structural and political barriers threaten to delay for years the introduction of affordable, generic LEN-LA at scale. This project, a collaboration between MSF and civil society partners, aims to dramatically accelerate introduction and scale up of long acting anti-retrovirals (LA-ARV) for HIV prevention within and beyond MSF programs. The collective will: 1: implement a community-led approach to advocacy for ARVs; 2: Secure enabling national policy environments regarding LEN-LA and other LA-ARVs in key geographies (India, Brazil, South Africa); 3: Challenge and change the most harmful aspects of patent holders’ voluntary license and overall access strategy; and 4: Advocate for appropriate technical and financial resources to support LA-ARV introduction, procurement, and supply.
To improve efficiency and enable standardization, mutualization and interoperability capacities between European Supply Centres (ESCs) and between ESCs and OCs, MSF Logistique and MSF Supply are collaborating to identify, test, evaluate and select a new Information Management System and prepare for its deployment. The output of this initial phase will be the selected vendor/software solution and a business case that includes estimated implementation cost, timeline, resources, approach, risks and risk mitigation.
The project aims to align MSF’s logistics practices by transforming fragmented standards into a unified, intersectional system that enables safe, consistent, and interoperable field practices across all Operational Directorates (ODs). MSF operates in over 70 countries, yet the technical guideline underpinning their work remains inconsistent and misaligned between ODs creating duplications and inefficiencies, particularly in contexts where multiple ODs operate side by side. In phase I (not supported by the TIC), standard and policies for five technical families – energy, fleet, biomed, cold chain and waste management were co-developed and validated by all ODs, confirming a need for a shared operational foundation. This second phase aims to shift from a proof of concept to an ambitious and practical system that logisticians can use daily. It will enable interoperability across ODs , reduce duplication of efforts, harmonize standards and bring efficiency in teams’ daily work. Focusing on telecom, sanitation, vector control and safety, the project will harmonize policies and shift from static PDFs to an interactive digital format that is searchable, multilingual and designed for field use. Pilot testing and field consultations will be built into the process through training, coordination weeks, and selected mission pilots.
The Learning Content Management Strategy and System project aims to create a cohesive and efficient framework for managing and sharing learning resources that can be adapted and reused across MSF. Led by the Intersectional Training and Learning Platform (ITL), the project aims to create a shared digital environment where users can access, visualize, analyze, and (re)use the full range of learning content available in MSF. The project will develop a framework and governance model (shared processes, workflows, standards, and tools) that organizes the contribution and collaboration among the different entities engaged in learning content management. The goal is more efficient and effective management of learning content thanks to a system that facilitates the seamless sharing of learning contents across MSF, both at HQ and countries of operation (and with other organizations), promoting collaboration, accessibility and ensuring more adapted and contextualized learning solutions.
Reduce barriers to appropriate and dignified healthcare by transforming how LGBTQ+ patients are welcomed and treated in MSF health projects through increased organizational literacy and competencies by developing multiple tools for field use and training modules for medical providers, leveraging best practices and other MSF models.
Address malaria morbidity and mortality by developing an Early Warning System (EWS) using predictive epidemiology and publicly available environmental data through machine learning. Detecting evolving patterns of Malaria, especially in low resources countries like South Sudan remains a major public health challenge. The current surveillance system limitation combined with rapid climate changes, underscore the urgent need to better anticipate malaria disease burden, within an operational feasible time frame. The project anticipates malaria trends and pilots EWS implementation in OCA lead Lainken Project in South Sudan and one site in another country. MSF can better adopt decision making process, timely intervention, targeted resource allocation, better coordination, community engagement and ultimately reduce morbidity and mortality. The project builds upon 2.5 years of MSF UK Sampling Nursery efforts where machine learning EWS has successfully forecasted malaria trends up to two months in advance.
Address the devastating impact of malaria, the single largest pathology treated by MSF, by piloting a new malaria vaccine R21 in the health region of Maradi, Niger before the seasonal peak. Conduct a cluster randomized trial of the vaccine, document the coverage, feasibility, and acceptability of two different implementation strategies, as well as their costs and operational footprints, to better inform eventual decision-making, have a seat at the table to leverage R21 for access, and to influence policy recommendations.
The current standard ready-to-use therapeutic food (RUTF) formulation may be insufficient to restore physiological and immunological resilience and contribute to the risk of relapse. Management of acute malnutrition needs new RUTF formulations to address the high risk of relapse more efficiently. This project will evaluate a new microbiome-directed food (MDF) that aims to improve the gut microbiome and improve programmatic outcomes, including relapse, in children with uncomplicated severe acute malnutrition. The new milk-free product could also, in addition to the expected clinical benefits, offer an alternative to RUTFs that can be produced locally. The randomized controlled trial will enroll 3,678 children aged 6 to <24 months with uncomplicated severe acute malnutrition (SAM) at 4 outpatient treatment centres in Niger.
Deploy and test “field medical simulation based learning solutions” that can be effectively used at field level by trained supervisors with the support of the mission’s HR & Medical Dept’s and Learning Unit.
Address MSF’s gender gap in leadership (women make up ~30% of MSF’s locally recruited staff) by promoting access to employment and professional development for women. Test actions to promote women employment and their access to leadership positions through organic women initiatives in coordination with field teams, with the support of operational cell, general management, and the associative representation of MSF -France. Focus on 2 countries of intervention: Niger and Mali to maintain a tight, pragmatic scope. Leverage women’s networks to facilitate feedback, articulate barriers and work towards potential solutions.
Address the critical challenge with non-medical hazardous waste management in South Sudan by developing an integrated, sustainable approach. Collaborating with the Juba Intersectional Waste Area (JIWA) and local stakeholders, this initiative aims to segregate, safely store, and reduce waste volumes, ensuring protection of MSF staff, environmental compliance and long-term sustainability. Pilot transformative solutions to manage non-medical hazardous waste, establish operational protocols, and create a replicable waste management framework scalable across MSF. With over five tons of lead-acid batteries and 600kg refrigerant equipment accumulated in a single MSF project in South Sudan, effective waste management for non-medical waste is crucial. The project has three phases: Phase 1 focuses on feasibility, waste assessment, process refinement; Phase 2 on implementation; and Phase 3 on capitalization, including Standard Operating Procedures development and establishing an integrated national management plan for MSF.
Provide MSF medical managers with a user-friendly, simplified tool (algorithm) that enables them to identify patient palliative care needs in their project and determine what type(s) of Palliative Care can be embedded into their project from a programmatic / operational perspective (home-based care, ambulatory, inpatient, mixed, etc.). Create a network of specialists trained to join MSF telemedicine service for Palliative Care clinical questions.
Rising resistance to key drugs used in TB treatment (such as bedaquiline, linezolid, clofazimine, delamanid, and pretomanid) is creating an urgent medical and public health crisis. This project aims to establish a Pre-Approval Access (PAA) Framework to enable timely, ethical, and safe access to investigational TB medicines for patients with expanded drug resistance, who currently have no effective treatment options. The project will build on MSF’s strong expertise developed through the PAA program implemented between 2011-2017. This mechanism is expected to provide potentially life-saving treatment to approximately 120 patients by the end of the project. The initiative will begin in MSF sites in high-burden settings (Afghanistan, Belarus, DRC, India, Myanmar, Uzbekistan, Pakistan) and progressively expand to partner organizations and countries participating in the Unitaid-funded Arc-TB project (Pakistan, Liberia, Kazakhstan Peru, South Africa). Ultimately, the project aims to catalyze the creation of a sustainable and scalable global platform for pre-approval access to investigational TB drugs and potentially adaptable to other diseases, while preparing from the outset for its handover to relevant technical agencies and donors.
Bearing witness and speaking out, with and on behalf of patients are fundamental to MSF’s mission, yet with MSF’s growth, a gap has emerged between content production and content dissemination. Communications staff in the field and at HQ have little knowledge on how the stories performed and whether they reach the intended audiences. To enable a holistic view of MSF‘s global communication reach and impact, the project will explore the use of Artificial Intelligence (AI) and Large Language Models (LLM). The first phase will assess current tracking of MSF communication initiatives, explore external solutions within and outside the sector and propose a roadmap for measuring the performance of MSF communications. If successful, a Phase II would focus on tool design and roadmap implementation.
Mitigate the environmental impact due to the use of single-use items and their packaging in the context of OCG medical operations by orienting procurement towards more sustainable alternative products and improving rational use when no viable alternative is available. To priorities efforts, the project will develop a pragmatic framework with a clear list of criteria to apply when reviewing single use products, their packaging and related practices in terms of environmental impact.
A scanning and reading technology integrated in a mobile application that will be collecting item information using 3 technologies: QR Code, Data Matrices and Optical Character Recognition (OCR) and integrated in all nodes of the international medical supply chain, from European Supply Centers (ESCs) to field projects.
This project aims to create a unified supply network in East Africa to optimize the use of MSF resources and reduce activity duplication in existing structures in the region: Support Unit Kampala (SUKA), Kenya Supply Unit (KSU) and other European Supply Centres (ESC)/OCs. Phase 1 is focused on redesigning the distribution network for a specific list of 80 large volume items such as ringer and gloves, for delivery to missions in East Africa with a better total cost of ownership (goods and transport). Four workstreams include (1) legal, (2) process & product quality,(3) financial and (4) order flow, supporting the future set-up frame.
MSF works in dynamic and often extremely challenging contexts where the softer aspects of caring for patients can sometimes be overlooked, yet the importance of fostering a supportive and compassionate relationship between staff of a health facility and patients cannot be overstated. There is strong evidence that supportive relationships among health workers directly improve the quality and safety of care. This project will aim to effectively improve supportive relationships in care at project level through interventions that lead to a demonstrated change in people, interactions and practice. The project will develop and test a full intervention package including an assessment for doctors and patients, training facilitators, hosting workshops and testing the approach in four pilot sites.
Address TB as a major cause of morbidity and mortality in children by testing and implementing new WHO recommendations within MSF, advocating internationally, and conducting operational research on potential impact in the field. Improve diagnosis, treatment, and prevention of TB by implementing new algorithms and treatment regimes, in collaboration with WHO – ultimately leading to a reduction in mortality. The recent WHO recommendations present a unique window of opportunity to transform the way that children are diagnosed and treated with TB across MSF projects. If successful, prepare a large-scale business case for scaling.
Transform OCB fleet management by embedding safety, sustainability, and strategic vehicle movement data use into operational practices. OCB alone operates a fleet of approximately 1,300 vehicles, yet no centralized fleet management system currently exists in MSF. In 2024, OCB consumed 2.4 million liters of fuel, contributing to 5% of its total CO2 emissions, and reported 44 moderate to severe road accidents. The project aims for a strategic shift from a fragmented, ad-hoc vehicle oversight model to a unified, data-driven approach. It will focus on four interlinked thematic areas: 1) vehicle usage rationalization, 2) fleet optimization and maintenance, 3) data-driven behavior change, and 4) policy development and standardization. Pilot testing will be conducted across two operationally diverse contexts, DRC and Ethiopia.
Address inefficiencies in contextualizing and resourcing (neglected diseases such as Dengue, Chagas; challenges in patient- and community-centricity; complex OC HR policies, gap in regional procurement) by fostering a culture of shared resources and capabilities in Latin America. Redesign resource sharing between MSF Brazil, MSF LAT, and CAMEX/CAMINO to gain efficiency, improve collaboration, and lay the groundwork for a future Operational Directorate in the Americas (ODA) in 2026.Review organizational set-up across the three sections to align regional investments with strategic priorities, optimizing resources in HR, Medical, Supply, Advocacy and Analysis, and Associative Leadership. Optimize shared resources for collective priorities. Leverage Latin America’s operational knowledge and experience across MSF. Share capacities to maintain the expenditure ratio on direct assistance while reducing overhead through mutualized services.
The “Vulnerable Too” initiative, led by the Mentoring and Coaching Hub at MSF Norway, proposes the creation of a digital platform where MSFers can share their experiences, express vulnerability, and find solidarity. It will create a secure, anonymous, and non-institutional platform grounded in storytelling and peer connection. It complements existing resources, but its heart is different: not compliance or treatment, but recognition, community, and care. Key features of the platform include: an encrypted submission system to ensure security and provide anonymity; a moderated peer-support forum; multimedia components providing access to diverse voices; integrated support, and a moderation chatbot.
